![]() Bum Friend – Spawns a familiar that collects nearby coins and potentially drop a random pick-up.Bucket Of Lard – +2 Health Up and Speed Down.Brother Bobby – Spawns a familiar that shoots 3.5 tear damage.Broken Watch – Upon entering a new room, there is a chance all enemies will be sped up or slowed down.Brimstone – Beam attack in place of tears.Butter Bean – Farts on nearby enemies and knocks them away from the player.Breath Of Life – Immune to tear damage for a certain amount of time.Box Of Spiders – Spawns 2-4 friendly critters.Boomerang – Stuns and damages foes that it is thrown at.Book Of Shadows – Grants invulnerability for 10 seconds.Book Of Secrets – Players obtain any of these three items: Treasure Map, Compass, or Blue Map.Book Of Revelations – Adds 1 soul heart and increases the chances for the boss to be a horseman.Book Of Belial – Damage Up for the current room only.Bob’s Rotten Head – Poisons and damages all foes it is thrown in the vicinity of.Blood Rights – Revokes a single half-heart from the player to damage all enemies in a room.Box – Grants a card, pill, and trinket.Bomb Bag – Spawns a familiar that drops bomb pickups every few rooms.Bogo Bombs – All bomb pick-ups contain 2 bombs.Bobby-Bomb – Grants 5 bombs with homing effect.Bob’s Curse – All bombs have a poisoning effect.Bob’s Brain – Spawns a familiar that launches in the direction you shoot at that explodes on contact with enemies.Blue Map – Reveals the current and future locations of Secret Rooms and Super Secret Rooms. ![]() Blue Cap – Health Up, Tears Up, and Shot Speed Down.Bloody Lust – Damage Up for the rest of the floor when the player takes damage.Blank Card – Stacks the same effect as current card in hand.Black Candle – Evil Up – grants curse immunity.Black Bean – Causes the player to fart poison gas when they take damage.Big Fan – Spawns an orbital that blocks shots and deals contact damage.BFFS! – All of the player’s familiars become larger, giving them bigger damage radius.Best Friend – Distracts enemies as a doll that explodes.Best Bud – Spawns a fly orbital when the player takes damage.BBF – Spawns a respawn-able familiar fly that explodes on contact with enemies.Battery – Usable items can now be overcharged.Tears can now possibly trigger slowing enemies and their projectiles down. Ball of Tar – Leaves a trail of tar behind the player that slows enemies and projectiles.Ball Of Bandages – Spawns an orbital that can evolve, granting a chance of charming enemies.Aries – Speed Up and grants the player to deal damage upon enemy contact.Aquarius – Leaves a trail of tears behind the player that deals damage to enemies.Anti-Gravity – Anti Gravity tears and Tears Up.Anemic – Range Up and grants Isaac toxic blood.Anarchist Cookbook – Spawns 6 troll bombs randomly.Abel – Spawns a familiar that mirrors the player’s movements and shoots in the opposite direction.Abaddon – Gives you 6 black hearts and tears now have the possibility of inflicting fear.3 Dollar Bill – Randomizes your tears for every room.20/20 – The player now shoots two tears.1Up – Grants an extra life to the player.?’s Only Friend – Spawns a controllable familiar fly.This guide is a work in progress to compile all of the passive/useable items in the game. ![]() Here are all 341 items in the game and their exact usages.
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